New modelPress · The Decoder
Google DeepMind Unveils AlphaGenome 2 to Predict Gene Changes in Specific Cell Types
Google DeepMind has released AlphaGenome 2, an AI model that predicts gene changes in specific human cell types. It finds nearly twice as many relevant gene variants as its predecessor. It is currently available only for noncommercial research.
- Every cell has the same DNA, but different cell types switch different genes on or off.
- The model takes a DNA sequence and a specific cell state as input and calculates the effect on that cell.
- It also predicts how DNA is packed inside the nucleus and DNA methylation, chemical tags that switch genes off or on.
- It was trained on over 107 million individual cell profiles from 68 tissues.